Studying cellular deliveries

5 years ago
Anonymous $ZPWJA6-QD2

https://phys.org/news/2018-10-cellular-deliveries.html

The authors had previously demonstrated how short, secreted RNAs can help other cancer cells grow and spread. In their latest work, they show that longer RNAs that either do or do not code for proteins can be secreted by cancer cells in specific ways.

In cancer cells with mutations in the KRAS gene, many of the secreted vesicles delivered mRNA coding for a protein called Rab13 to new cells. Rab13 may play a role in regulating what RNAs are exported in vesicles but is also commonly found in cells that resist radiation therapy, and therefore may be involved in helping cancer cells be more aggressive.