https://www.vox.com/the-highlight/24105096/crispr-gene-editing-theory-dna-diversity

The genetic data that underpins CRISPR has a big diversity problem.

Medicine has entered a new era in which scientists have the tools to change human genetics directly, creating the potential to treat or even permanently cure diseases by editing a few strands of troublesome DNA. And CRISPR, the gene-editing technology whose creators won the Nobel Prize for Chemistry in 2020, is the face of this new normal.