https://www.cnet.com/news/growing-food-brewing-beer-and-making-stuff-in-space/

Like early explorations of Asia and the New World centuries ago, expeditions to Mars will last years. Depending on Mars' position relative to Earth's orbit, it will most likely take about nine months just to get there. But arriving will be only the beginning. Those pioneering astronauts will have to spend another 500 days on the red planet until its orbit aligns with Earth's, then travel nine months again to return home. So what do we have to do to keep them well-supplied and healthy?

NASA researchers and various companies are working on ways to grow nutritious leafy greens, make spare parts on the fly (literally), brew drinks -- even develop tech that repairs itself -- to help astronauts go years without outside help.