http://www.sciencemag.org/news/2018/07/troubling-questions-remain-about-whether-popular-hiv-drug-causes-birth-defects

As part of a program aimed to prevent mother-to-child transmission of HIV, outreach workers in Francistown, Botswana, staged a skit in a supermarket parking lot.

Dolutegravir, which enjoys a reputation as the best of 32 marketed antiretroviral drugs, took a serious hit in May when a preliminary analysis from a study that included more than 10,000 HIV-infected pregnant women in Botswana revealed it may lead to serious birth defects. Today, at the International AIDS Conference in Amsterdam, researchers reported more data from that study that suggest the risk of harm may be lower than first thought. But troubling questions remain about its safety during pregnancy and whether programs that plan to promote it widely should restrict its use in women of child-bearing age.